{"id":405,"date":"2010-08-05T16:03:45","date_gmt":"2010-08-05T16:03:45","guid":{"rendered":"http:\/\/labrigger.com\/blog\/?p=405"},"modified":"2010-08-05T17:00:13","modified_gmt":"2010-08-05T17:00:13","slug":"lavaamp-minipcr","status":"publish","type":"post","link":"http:\/\/labrigger.com\/blog\/2010\/08\/05\/lavaamp-minipcr\/","title":{"rendered":"LavaAmp: miniPCR"},"content":{"rendered":"<p align=\"center\"><a href=\"http:\/\/lavaamp.wordpress.com\/\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/labrigger.com\/blog\/wp-content\/uploads\/2010\/08\/lavaamp1.jpg\" alt=\"\" title=\"lavaamp1\" width=\"500\" height=\"333\" class=\"aligncenter size-full wp-image-406\" srcset=\"http:\/\/labrigger.com\/blog\/wp-content\/uploads\/2010\/08\/lavaamp1.jpg 500w, http:\/\/labrigger.com\/blog\/wp-content\/uploads\/2010\/08\/lavaamp1-300x199.jpg 300w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/a><\/p>\n<p><a href=\"http:\/\/lavaamp.wordpress.com\/\">LavaAmp<\/a> is a thermocycler (aka <a href=\"http:\/\/labrigger.com\/blog\/tag\/pcr\/\">PCR machine<\/a>) that promises to bring <a href=\"http:\/\/en.wikipedia.org\/wiki\/Polymerase_chain_reaction\">PCR<\/a> to the masses. The aim is to have it available by <a href=\"http:\/\/lavaamp.wordpress.com\/about\/#comment-8\">1Q 2011 for about $400<\/a>. <a href=\"http:\/\/www.synthesis.cc\/2010\/02\/bits-atoms-and-the-future-of-manufacturing.html\">This post<\/a> at Synthesis.cc has more details on the engineering: <\/p>\n<blockquote><p>We continue to refine the hardware design of the LavaAmp, and it looks like we have the production hardware down to 5 or 6 components, 4 of which are injection molded plastic.  The labor will only be in assembly of the final box, as all sub-assemblies should all come off automated fab lines of one kind or another.  All the real cost is in the design and tooling &#8212; once we get up and running the per unit costs should be quite reasonable.<\/p><\/blockquote>\n<p>Update on <a href=\"http:\/\/labrigger.com\/blog\/2010\/06\/17\/openpcr\/\">OpenPCR<\/a>: This similar effort is making progress as well. Their funding round was wildly successful, generating 202% of their goal!<\/p>\n<p>The relatively recent expiration of several PCR patents help make these projects possible (<a href=\"http:\/\/openpcr.org\/2010\/06\/pcr-patents-are-dead\/\">OpenPCR writes about this<\/a>). The democratization of this technology is important, as Guido from LavaAmp describes (<a href=\"http:\/\/scienceblogs.com\/grrlscientist\/2010\/03\/lavaamp_the_amazing_handheld_t.php\">via<\/a>):<\/p>\n<p><object width=\"640\" height=\"513\"><param name=\"movie\" value=\"http:\/\/www.youtube.com\/v\/VQuIUjhW4VA&amp;hl=en_US&amp;fs=1\"><\/param><param name=\"allowFullScreen\" value=\"true\"><\/param><param name=\"allowscriptaccess\" value=\"always\"><\/param><embed src=\"http:\/\/www.youtube.com\/v\/VQuIUjhW4VA&amp;hl=en_US&amp;fs=1\" type=\"application\/x-shockwave-flash\" allowscriptaccess=\"always\" allowfullscreen=\"true\" width=\"640\" height=\"513\"><\/embed><\/object><br \/>\n(<a href=\"http:\/\/www.youtube.com\/watch?v=p7duHMxQYNQ\">Espa\u00f1ol<\/a>)<\/p>\n<p>What is also needed is a cheap source of reagents and supplies for molecular biology. A PCR machine isn&#8217;t much use if you can&#8217;t afford polymerase. Molecular biology labs blow most of their budgets on consumables, not equipment. This isn&#8217;t a criticism of the LavaAmp and OpenPCR projects, which are very important. I hope they catalyze a renewed, broader effort to democratize biotech.<\/p>\n","protected":false},"excerpt":{"rendered":"<p align=\"center\"><a href=\"http:\/\/lavaamp.wordpress.com\/\"><\/a><\/p>\n<p><a href=\"http:\/\/lavaamp.wordpress.com\/\">LavaAmp<\/a> is a thermocycler (aka <a href=\"http:\/\/labrigger.com\/blog\/tag\/pcr\/\">PCR machine<\/a>) that promises to bring <a href=\"http:\/\/en.wikipedia.org\/wiki\/Polymerase_chain_reaction\">PCR<\/a> to the masses. The aim is to have it available by <a href=\"http:\/\/lavaamp.wordpress.com\/about\/#comment-8\">1Q 2011 for about $400<\/a>. &#8230;<\/p>\n<div class=\"read-more\"><a href=\"http:\/\/labrigger.com\/blog\/2010\/08\/05\/lavaamp-minipcr\/\">Read More<\/a><\/div><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[8],"class_list":["post-405","post","type-post","status-publish","format-standard","hentry","category-hardware","tag-pcr"],"_links":{"self":[{"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/posts\/405","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/comments?post=405"}],"version-history":[{"count":12,"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/posts\/405\/revisions"}],"predecessor-version":[{"id":416,"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/posts\/405\/revisions\/416"}],"wp:attachment":[{"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/media?parent=405"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/categories?post=405"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/tags?post=405"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}