{"id":4250,"date":"2015-04-23T14:22:11","date_gmt":"2015-04-23T18:22:11","guid":{"rendered":"http:\/\/labrigger.com\/blog\/?p=4250"},"modified":"2015-04-23T14:22:11","modified_gmt":"2015-04-23T18:22:11","slug":"new-spike-inference-for-sima","status":"publish","type":"post","link":"https:\/\/labrigger.com\/blog\/2015\/04\/23\/new-spike-inference-for-sima\/","title":{"rendered":"New spike inference for SIMA"},"content":{"rendered":"<p align=\"center\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/labrigger.com\/blog\/wp-content\/uploads\/2015\/04\/spike_inference.png\" alt=\"spike_inference\" width=\"600\" height=\"451\" class=\"alignnone size-full wp-image-4251\" srcset=\"https:\/\/labrigger.com\/blog\/wp-content\/uploads\/2015\/04\/spike_inference.png 600w, https:\/\/labrigger.com\/blog\/wp-content\/uploads\/2015\/04\/spike_inference-300x226.png 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>Following up SIMA, <a href=\"http:\/\/labrigger.com\/blog\/2014\/10\/09\/sima-image-analysis-from-the-losonczy-lab\/\">which has been covered here before<\/a>:<\/p>\n<p>The SIMA team has released a new version of its toolbox that includes a spike inference algorithm developed by <a href=\"http:\/\/www.stat.columbia.edu\/~eftychios\/Home\/Home.html\">Eftychios Pnevmatikakis<\/a> and <a href=\"http:\/\/www.stat.columbia.edu\/~liam\/\">Liam Paninski&#8217;s<\/a> group. This approach permits the efficient estimation of the most likely spike train underlying a sequence of calcium imaging observations.<\/p>\n<p>The new algorithm improves upon earlier work in two significant ways:<br \/>\n\u2013 Parameter estimation has been significantly improved to achieve good performance out of the box on many different kinds of calcium imaging data.<br \/>\n\u2013 The algorithm can take advantage of standard conic optimization solvers (like <a href=\"https:\/\/mosek.com\/\">Mosek<\/a>) to run very fast.<\/p>\n<p>The new toolbox can be <a href=\"https:\/\/pypi.python.org\/pypi\/sima\">found here<\/a>, or <a href=\"http:\/\/www.losonczylab.org\/sima\">here<\/a>, or <a href=\"https:\/\/github.com\/losonczylab\/sima\">here<\/a>.<\/p>\n<p>Further details about the algorithm can be read <a href=\"http:\/\/arxiv.org\/abs\/1409.2903\">in this preprint<\/a>.<\/p>\n<p><em>Post by Tim Machado.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p align=\"center\">\n<p>Following up SIMA, <a href=\"http:\/\/labrigger.com\/blog\/2014\/10\/09\/sima-image-analysis-from-the-losonczy-lab\/\">which has been covered here before<\/a>:<\/p>\n<p>The SIMA team has released a new version of its toolbox that includes a spike inference algorithm developed by <a href=\"http:\/\/www.stat.columbia.edu\/~eftychios\/Home\/Home.html\">Eftychios Pnevmatikakis<\/a> and <a href=\"http:\/\/www.stat.columbia.edu\/~liam\/\">Liam Paninski&#8217;s<\/a>&#8230;<\/p>\n<div class=\"read-more\"><a href=\"https:\/\/labrigger.com\/blog\/2015\/04\/23\/new-spike-inference-for-sima\/\">Read More<\/a><\/div><\/p>\n","protected":false},"author":1,"featured_media":4251,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[25,38],"class_list":["post-4250","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-software","tag-analysis","tag-calcium-imaging"],"_links":{"self":[{"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/posts\/4250","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/comments?post=4250"}],"version-history":[{"count":3,"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/posts\/4250\/revisions"}],"predecessor-version":[{"id":4254,"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/posts\/4250\/revisions\/4254"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/media\/4251"}],"wp:attachment":[{"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/media?parent=4250"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/categories?post=4250"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/labrigger.com\/blog\/wp-json\/wp\/v2\/tags?post=4250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}