Roger Tsien’s lab recently published the new generation voltage sensitive dye they were presenting at SfN: VoltageFluors. As often when then Tsien Lab takes on a new field, they start by taking a completely new approach….
Nature just published a 4-page perspective article on the important of releasing the source code for programs used in scientific research. The authors emphasize the importance of reproducibility for results that depend…
Perhaps you’re familiar with the various AOD and piezo-based methods for two-photon imaging in 3D quickly. Here’s another way (Botcherby et al. 2012, PNAS, open access)
The used all galvos, rather than AODs or piezo…
Intrinsic signal optical imaging is a functional imaging modality where the reflectance of red light indicates active portions of cortex. It is used for many applications, including imaging individual barrels in rodent somatosensory cortex, maps in visual cortex, and the tonotopic organization in auditory cortex.
Here is a prior Labrigger post with tips for intrinsic…
The main factor that limits how deep we can image into tissue is the scattering of light. Multiphoton imaging partially mitigates the problem by using infrared light, which scatter less, and by using an excitation process…
Perhaps you’ve heard about the Elsevier Boycott aka the Cost of Knowledge. I’m not going to rehash the problem we all know so well. But here are a few links I wanted to share. Just…
There are some open access journals that seem to have relativley loose editorial standards. And by “editorial” I mean “ethical”, and by “relatively loose”, I mean “no”. These publishers have been called “predatory” open access…
The Open Microscopy Environment (OME) is a group of programmers, from academia and industry, who put together open source software packages for managing microscopy data. The emphasis is on handing multiple image formats, organizing them,…
OpenElectrophy is a somewhat mature, actively developed, open source program for analyzing data from multielectrode recordings. It makes heavy use of Python and SQL and is developed by a team of French researchers including Samuel…
Thorlabs and Newport have offered 3D models of their products for a long time. However, they’re typically in formats for expensive programs like SolidWorks and AutoCAD. In the past year or two, Newport has been slowly adding to their library of Google SketchUp models.
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Like many of you, I went to monster truck show last weekend.
The competition reminded me MATLAB’s new thing: Cody.
It’s a bunch of problems posed as MATLAB coding tasks. For example:
Find the mean of each…
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