I saw this post, with this quote: “High-resolution activity maps of PFC did NOT align with cytoarchitecturally defined subregions.” Is this a profound, provocative finding that provides strong evidence for the irrelevance of cytoarchitecture?
One of the most common ways that universities and institution use to evaluate scientists is to solicit letters of recommendation. But who should they ask? Of course former mentors will write letters. To…
Lisa Saksida and Tim Bussey turned touchscreen systems into high throughput tools for rodent behavior assays. When I visited their lab in Cambridge (they’re now based at U Western Ontario in London, Canada, between…
CRISPR/Cas9 technology has greatly accelerated the development of genetically engineered mice, but it’s still a big investment of time before the mice are ready. For quicker turnaround, there are other options (and speed isn’t…
In this work, the authors used fast optical motion tracking and 2p imaging to measure the activity of individual neurons in freely moving animals. No surgery. No optical window. No restraint. And all the…
Andre and colleagues have a preprint up on their project generating inexpensive instrumentation for imaging and optogenetics experiments. The 100 Euro Lab: A 3-D Printable Open Source Platform For Fluorescence…
Pixy is an open source computer vision system. Mostafa Nashaat, Robert Sachdev, and colleagues including Matthew Larkum have developed software for use with the Pixy, that can be used to track mouse behavior, including free movement…
Results are similar to the slow version of TurboReg, but it runs about twice as fast as the fast version of TurboReg.
Here’s the paper.
Here’s the code.
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Bar-Noam et al. 2016 (Shy Shoham’s lab) figured out how to image the mouse retina with 2-photon microscopy in vivo.
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I tweeted about this last fall. This is the best algorithm I’ve seen for segmenting and extracting time course from calcium imaging data. Eftychios Pnevmatikakis developed the code in Liam Paninski’s lab….
In the past, Labrigger has only rarely posted about relevant papers. That ends today. Now there’s a new post category for papers, and it’ll be used to highlight publications that are of potential interest to…
