aBioBot is an open source liquid handling (i.e., pipetting) robot platform with integrated machine vision. The system can deal with multiple tube types, and detect if a tip falls off. It also has an extensive web-based protocol authoring and monitoring software package.
“> Leonardo Lupori and Raffaele Mazziotti are two fellows in lab of the excellent Tommaso Pizzorusso. They have developed an intrinsic signal optical imaging rig and are sharing all of the materials. Here’s their web site with the resources and links. More on intrinsic imaging… Yet more again…
Experiment rooms can get noisy, so Labrigger puts the noisy bits in sound dampening cabinets like these. A separate room could be ideal, but this works too. Just put all the noisy equipment (rackmount portions of Ti:Sapph laser systems, water chillers, or anything with noisy fans). There are lots of resellers. The one we used
ScanImage 5 supports resonant scanning with a wide range of hardware. So custom rigs can add resonant scanning pretty easily, while sticking with ScanImage for acquisition. It takes about $10,000 worth of electronics from National Instruments. In addition, you’ll need the resonant and galvo scanners themselves. From Cambridge, resonant scanners are under $2000, and conventional
Our friend Christian Wilms tipped us to Austin Blanco’s blog, which has some posts you all might be interested in: Characterizing unknown optical components A few notes on Arduinos, their timers, and using them with rotary optical encoders Long-term considerations when buying or building and imaging system Surprisingly clean +/- 5 volts from USB or
Theo Walker has a very nice open syringe pump design that has some advantages over another open syringe pump project we’ve covered (though the latter is less expensive).
About 25 years ago, pro-level audio recording technology was prohibitively expensive for home studios. Then, digital audio technology like the Alesis ADAT enabled working class musicians to produce high fidelity recordings. The fast development of audio recording technology has pushed prices down and performance up to a point where 24-bit/192kHz digitizer kits are cheap, and
OpenTrons is a project to develop an open architecture for liquid handling lab robots. Actually, they’re more versatile than that. They can also be used for related robotic tasks, such as pick-and-place machines. They already have BioBot 1.0 available: parts, plans, and directions are all online. Open Electronics has an interview with OpenTrons’ Will Canine.
OpenLabTools is a new initiative at Cambridge University, using engineering students to develop modular lab equipment. The OpenLabTools initiative aims to provide a forum and knowledge centre for the development of low cost and open access scientific tools, with an emphasis on undergraduate and graduate teaching and research. The programme is developed thanks to contributions
Mobile HomeCage is a different approach for awake, behaving experiments. It’s from Helsinki-based Neurotar. Their marketing video is worth a viewing. You won’t regret it.
From Andrew Hires’ twitter— repurposing an old hard drive for beveling pipettes. Nice! Hat tip to Tobias Rose.
Jacob Forstater (UNC-Chapel Hill, Physics) shared this tip: The Klavins lab is sharing their materials for this open source turbidostat. The wiki offers detailed plans and well-document construction. Even if you don’t need a turbidostat, it’s interesting to look through because it includes several interesting components, including a syringe pump. They recently set up to
Labrigger previously mentioned this contest. All of the 173 projects are online for your perusal. See if any of them inspire you.
- GCaMP6 now available on
- Sourcing small parts on
- Analysis algorithms: performance quantification and ground truth on
- Laser pointers and quantum mechanics on
- Pixy for easy Arduino machine vision on
- Constrained non-negative matrix factorization for calcium imaging data analysis on
- Series resistance in patch clamp experiments on
- Checking PMT performance over time on
- GCaMP6 reporter mice on
- GCaMP6 reporter mice on
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