Monthly archives: September, 2010

Optomechanics for a custom 2p uncaging rig

Post by Darcy Peterka (Columbia University/Yuste lab):

We do a bunch of multiple imaging/uncaging experiments with 2+ lasers, and got tired of constantly taking apart the camera/laser ports to switch lenses and dichroics. This setup allows…



Citizen science article in NN

Nature Neuroscience has a great article on citizen science in the September issue (link, subscription required).

In the article, they discuss that although the public already recognizes the value of publicly funded research, the priority…



3D Printed Equipment from the DeRisi Lab

The DiRisi Lab at UCSF shares their STL files for 3D printing some equipment. There’s a pipette holder, several gel combs, an objective case, and more. You can print your own with your…



Single cell electroporation workshop

Michael Hausser’s lab is having a single cell electroporation workshop in London November 1-2. (link)

The application deadline is Thursday, September 30, 2010.



DIY open access

Even if you publish in a “closed” journal, you are typically allowed to post the PDF of your article on your personal website.

For…



Open Science Summit videos

There are videos from the talks at the Open Science Summit online now. The topics include the OpenPCR and Otyp projects, open source drug discovery,…



Building a 2-photon microscope

Less than a year ago, the patent on 2-photon microscopy ran expired (Nov 14, 2009 pdf). So now anyone can sell a kit or system for two photon microscopy without having to pay a licensing fee.

If you don’t want to start from scratch, there are a lot of options.

Prairie Technologies



Open science

“Open” is a nice sounding word, not unlike “free”, that is used rather liberally whenever some bit of intellectual property is shared with the public. However, it can mean very different things in different…



Multichannel recording systems

This is just a quick list of manufacturers/vendors of multielectrode recording hardware, and their roots. Unsurprisingly, they were almost all started by neurophysiologists. It’s interesting how diverse they are, they each seem to have a…



Lasers for multiphoton microscopy

Coherent just sold its 1000th Chameleon system. That’s roughly how many of the similarly-priced Lamborghini Countach LP500s were sold. That was in the 1980s. Coherent has been selling Chameleons since 2003,…



Outfitting a lab on the cheap

A friend of mine does a lot of molecular biology and keeps an incubator at home so she can run a reaction and stop it some time at night without having to make a special…



Remote desktop software

From time to time, you might catch me on my yacht, running an imaging experiment by remote desktopping into my rig from my laptop. I would use my iPhone, but I can’t fit all the windows for ScanImage onto the screen, even with…



TIFFs in MATLAB

MATLAB uses the open source library libtiff to write TIFF files, or they did the last time I asked. I work with multipage TIFFs a lot, and I find MATLAB is not very fast…



Crowdsourcing your work

Ebird is a website where bird watchers (or “birders”, in the parlance of the field) upload their observations. This project, by Cornell’s Lab of Ornithology and the National Audubon Society, has been a beautiful…



Soft raw materials

A UK postdoc came to our lab in the US and was surprised that we didn’t have any Blu-Tack in the lab. His old lab wasn’t the only UK lab that goes through Blu-Tack…