Tag: electrophysiology

LabMaker – a retail source for some open source projects

LabMaker sells parts, kits, and assemblies for open source neuroscience tools, including the UCLA MiniScope and Crystal Skull “coverslips”.



Intan CLAMP Patch Clamp Amplifier Systems

Multiple people have asked for a discussion of Intan CLAMP patch clamp amplifiers. For those who are unfamiliar with them, they’re miniaturized patch clamp amplifiers. What looks like a headstage, is actually an entire…



Series resistance in patch clamp experiments

For teaching electrophysiology, there’s still a lack of comprehensive references. In particular, it can be difficult to impart to students an intuitive feel for the quality or fidelity of electrophysiological recordings. How close to the truth are those…



SpikeGadgets extracellular recording and open source software

SpikeGadgets makes hardware and software for extracellular array recording.

They make nice looking hardware, both for recording from arrays, and for controlling experiments.



Postdoc position with Duguid in Edinburgh

A world-class in vivo patch clamp electrophysiologist, Ian Duguid, is recruiting to his lab. Ian provides excellent training, and his lab is in a tremendous setting: Edinburgh. Ian’s also one of the current…



3D printed fly holder

Peter Weir has a nice write up and directions on how to make the fly holder from his recent paper. He has some other useful notes that are worth checking out too: github, blog, …



Open Ephys’ Cyclops LED driver

We covered Open Ephys back in 2013. They have well-developed devices for extracellular electrophysiology, and have some work on intracellular electrophysiology as well. Check out the Cyclops LED driver too. It continues to be an…



PackIO for NI devices

Adam Packer wrote some LabVIEW software for acquiring and generating data from National Instruments cards called PackIO. It is meant to trigger and synchronize equipment as well as record any data, with a few specific modules…



Course in Paris

The Optical Imaging and Electrophysiological Recording in Neuroscience course is Jun 9-19 in Paris. Application deadline is March 30. Lots of great people will be teaching, including Valentina Emiliani, Isabel Llano, Brad Amos, Troy Margrie,…



Python ephys and calcium imaging analysis code

Andrew Giessel wrote some analysis code in Python when he worked in the Datta lab. He has since moved on to another venture, but he open-sourced the code. There are import routines for data from ScanImage and Ephus,…



Patch clamp amplifier in chip form

See that metal box the pipette holder is attached to? That’s not a headstage, that’s the whole patch clamp amplifier. Reid Harrison is the lead author (co-senior authors are Craig Forest and Ed Boyden) on a …



Brain slice methods

Brain slice methodology is a mix of rational approaches, post hoc rationalized approaches, and plain black magic. This…



Measuring the junction potential

How to measure the liquid junction potential

This is an old blog post, but the comments section is still somewhat active. Handy reference/training material.



OpenPicoAmp: an open lipid bilayer amplifier

Up on arXiv just recently, is Shlyonsky, Dupuis, and Gall’s OpenPicoAmp. They pitch it as an educational tool, and that’s probably what it’s best suited for, but the recordings look nice. It’s a fun PDF to flip…



StimFit

Christoph Schmidt-Hieber and his collaborators Guzman and Schlogel have developed a cross platform (Linux, Windows, and OS X) application for analyzing electrophysiology data. Here’s the paper (open access). And here’s the code’s website.

A key…