Unenthusiastic about spending thousands of dollars on electrophysiology software like pCLAMP? Try the free and open source Strathclyde Electrophysiology Software. It’s a suite of programs for recording and analyzing signals from intracellular electrophysiology experiments. It’s for Windows. Many standard DAQs work right out of the box. Encouragingly, it has been updated routinely since 1997, including as recently as Jan 16, 2013.
The MATLAB-based Ephus, from the Svoboda lab, is another option. There are others as well (here’s a list), but these are the two open source, free options that seem to be regularly updated. Let me know if there are others.
I was raised on ephus and I really enjoy using it. JT says I’m probably the only guy out there that likes ephus however. I’ll have to check out strathcylde sometime.
Taro tools, which runs on Igor pro is pretty good for analysis. Datapro, written by the Spruston lab is also very good for analysis and acquisition.
Is there a web site for Datapro? I’ve seen it referenced in papers, but I haven’t seen it publicly released.
Nelson Spruston is the one who has developed it. If you really want to take a crack at using it you should probably contact him directly. I believe he is now at Janelia Farm. He was previously at Northwestern.
WinWCP and WinEDR are both really great. Together with some old NI PCI-6040e (90€ at ebay!) I’ve patched my masterthesis verry sucessfully, single channel and whole cell, and I will continou to use it now in iv-vivo multichannel single-unit recordings! But unfortunately there’s hardly something comparable for Linux. Maybe RELACS (http://relacs.sourceforge.net/).
Cheers!