Slack software for labs

Slack is very useful team coordination software. It’s been such a help in my own lab, that I suspect that given a properly configured Slack account, I could simultaneously run GE, Google, Intel, and the US…



Orange is open software for data exploration

Orange is a user friendly, graphical data mining package built with Python, from the University of Ljubljana. Check it out. They have a good blog for the project…



Meeting in Belgium on Read-Modify-Write Neural Circuitry

Neuro-Electronics Research Flanders is having its annual Neurotechnology Symposium May 2nd and 3rd, 2016 in Leuven, Belgium.
This year the focus is on “Read- Modify- Write” technologies for interfacing with neural circuits.

Confirmed Speakers:
Dora…



Enhancer trap mice from Brandeis

There’s a project in Sacha Nelson’s lab at Brandeis to generate and characterize enhancer trap mice for studying neural circuitry. They have a nice online searchable database of the lines they’ve generated,…



DIY 1060 nm fiber laser

For less than $13,000, you can build your own fiber laser and get pretty nice images with it.



moco, fast open-source motion correction for 2-photon calcium imaging movies

Results are similar to the slow version of TurboReg, but it runs about twice as fast as the fast version of TurboReg.

Here’s the paper.
Here’s the code.



Open source structured illumination MATLAB code

Peng Xi (Peking University) shared this resource his lab has developed: software for processing images for structured illumination (a superresolution technique).
Here’s the Github repository.
And here’s the paper…



DARPA: read 10^6 neurons, write 10^5 neurons

DARPA wants a dream neural interface. They can wait 4 years, but they want a complete plan now (abstracts due Feb 25, full proposals April 14).

This is a direct quote from the announcement for…



Open Ephys’ Cyclops LED driver

We covered Open Ephys back in 2013. They have well-developed devices for extracellular electrophysiology, and have some work on intracellular electrophysiology as well. Check out the Cyclops LED driver too. It continues…



2-photon calcium imaging of the mouse retina in vivo

Bar-Noam et al. 2016 (Shy Shoham’s lab) figured out how to image the mouse retina with 2-photon microscopy in vivo.



Constrained non-negative matrix factorization for calcium imaging data analysis

I tweeted about this last fall. This is the best algorithm I’ve seen for segmenting and extracting time course from calcium imaging data. Eftychios Pnevmatikakis developed the code in Liam Paninski’s lab….



New category of posts: papers

In the past, Labrigger has only rarely posted about relevant papers. That ends today. Now there’s a new post category for papers, and it’ll be used to highlight publications that are of potential interest to…



Open source head-mounted calcium imaging

The UCLA Miniscope project is an NIH BRAIN Initiative-funded project to open source head-mounted calcium imaging devices. Their web site is online now. They’ll be releasing all of the information needed for making these devices yourself, including data analysis. They’ll also…



Ufora – easy parallel computing in Python

It’s still early days, but this looks impressively good. Ufora might be one of the easiest-to-try ways to use parallel computing. With just a couple of lines of code, you can run…



CANDLE-J for denoising 2p data

Collaborative Approach for eNhanced Denoising under Low-light Excitation, or CANDLE, is a denoising algorithm specialized for the type of images that are acquired in 2-photon imaging applications. There’s code for both ImageJ and MATLAB…