We covered Open Ephys back in 2013. They have well-developed devices for extracellular electrophysiology, and have some work on intracellular electrophysiology as well. Check out the Cyclops LED driver too. It continues to be an active community as evidenced by their wiki and forum.
The UCLA Miniscope project is an NIH BRAIN Initiative-funded project to open source head-mounted calcium imaging devices. Their web site is online now. They’ll be releasing all of the information needed for making these devices yourself, including data analysis. They’ll also be holding workshops to train users. These devices compare favorably to commercial options. Inscopix
Microscopists are often adapting techniques pioneered for astronomy. Adaptive optics is the example you all probably know. Relatedly, phase retrieval was originally developed for telescopic imaging systems, and was adapted for high NA microscopic imaging systems by Mats Gustafsson and colleagues (Hanser et al. 2003 Optics Letters). A couple of excellent optics people, Kyle Douglass
“> Leonardo Lupori and Raffaele Mazziotti are two fellows in lab of the excellent Tommaso Pizzorusso. They have developed an intrinsic signal optical imaging rig and are sharing all of the materials. Here’s their web site with the resources and links. More on intrinsic imaging… Yet more again…
Many lasers have baseplates with channels through which chilled water is pumped to dissipate heat and stabilize the temperature of the system. I haven’t had much trouble with the chillers and baseplates of Newport/Spectra-Physics systems. However, most of the Coherent Chameleon systems I’ve worked with (3 out of 4) have had problems with the water
This from Matt Palmatier: Drug self-administration labs need swivels and there are plenty of medical devices (rotating luer fittings) that perform this function for pretty cheap. However, suppliers-that-shall-remain-nameless charge quite a bit for simple luer fittings that turn. For example, a disposable turning luer costs about $4. A drug self-administration swivel costs about $35. That’s
Labrigger has been experimenting with Raspberry Pis. We still find a lot of uses for Arduinos for little jobs around experimental rigs. Their simplicity and predictable performance (no background processes) make them easy to implement and reliable. Given how useful Arduinos have been, it stands to reason that something with more power, like a Raspberry
From Benjamin Judkewitz: I needed an IR viewer to see a Ti:S beam and was really surprised to find that most viewers still sell for > 1000 € (or $). Visualizing NIR used to be really simple with smartphones (enabling public installations like this one by JPL/NASA), but that was before nearly all makers started
In the talk I gave at the Short Course at SfN 2014, I briefly discussed the process of optical system design. A common strategy is to start with a published design, or at least a general scheme (series of lens types), and then make modifications to fit the target application. Finding these published designs can
Embrio isn’t completely open. They want to sell $50 licenses. Let’s get that out of the way first. However, it is an interesting alternative for programming Arduino hardware. It’s a visual programming environment, like LabVIEW. In some ways, it is richer than LabVIEW, and perhaps more comparable to MAX in that variable values can be
Experiment rooms can get noisy, so Labrigger puts the noisy bits in sound dampening cabinets like these. A separate room could be ideal, but this works too. Just put all the noisy equipment (rackmount portions of Ti:Sapph laser systems, water chillers, or anything with noisy fans). There are lots of resellers. The one we used
The Raspberry Pi 2 is here, and thus there are good deals on the Raspberry Pi B+. You’ll have to decide if any of these kits are a good deal for you. The Raspberry Pi 2 will be at the same price point ($35) as the prior generation. Anandtech has a nice rundown on this
It’s been promised for a while now, but someone has to do the hard work to make it happen. That inevitably involves some pretty pitiful looking stepping stones on the way to the promised land. So try to ignore the fact that this is among the worst looking 3D printed crap you’ve ever seen and
The Intel Galileo is an interesting mashup. It’s Arduino compatible. You can hand it to an undergrad and they can download the Arduino IDE and program it on their own with relatively little training. However, it’s also a 32-bit x86 SoC, so it’s running that Arduino sketch in one thread while having plenty of processing
Austin Blanco has designed and built an open-source system for controlling complex imaging systems called TriggerScope. It’s highly customizable out of the box, and both the firmware and software are open.
Tag cloud3d printing analysis arduino behavior calcium imaging collaboration computing construction course data acquisition dissemination electronics electrophysiology equipment fluorescence funding gadgets imaging jobs labview laser laser cutting machining manipulators materials MATLAB meeting microscopy openness optics osx pcr processing python references robotics two-photon video visual stimuli water jet cutting